Programme
Registration opens at 12:00 PM. The event begins at 02:45 PM, with the Plenary Lecture at 03:00 PM.
Wednesday, May 20
| From 12:00 PM- Registration |
| 02:45 PM- Welcome & Opening PE2026 – SALA NAUTILUS |
| 03:00 PM– Plenary Lecture Prof. Dr. Danijel Kikelj – “Paul Ehrlich MedChem Euro-PhD Network: A Permanent Inspiration” |
| Oral Communications (10 + 3 min Q&A) |
| 04:00 PM OC1 – Ewout Van de Velde Ghent University Generalized parallel synthesis and anti-trypanosomal evaluation of a chemically diverse 6-functionalized C-nucleoside compound library Author Information & E-Abstract |
| 04:15 PM OC2 – Ana Carolina Mazzochi Universidade de Santiago de Compostela Anti-Trypanosoma cruzi Potential of New Pyrazole-Imidazoline Derivatives Author Information & E-Abstract |
| 04:30 PM OC3 – Sara Damiani University of Ljubljana Synthesis and Investigation of Fluorinated Scaffolds Exhibiting Through-Space Scalar 19F –19F NMR Coupling Author Information & E-Abstract |
| 04:45 PM OC4 – João Sousa Janela Universidade de Coimbra New O-Prenylated Caffeic Acid Amides with Selective Toxicity Against Trypanosoma cruzi Amastigotes. Design, Synthesis and Structure-Activity Relationships Author Information & E-Abstract |
| Coffee Break |
| 05:30 PM OC5 – Laura Demuru University of Cagliari Identification, Design, and Optimization of New Allosteric Inhibitors Against ZIKV and WNV NS2B-NS3pro Author Information & E-Abstract |
| 05:45 PM OC6 – Leonardo Lemos University of Santiago de Compostela Synthesis, characterization and evaluation of anti-T. cruzi activity of 1-arylpyrazole-4-carboximade-N-propylimidazoles Author Information & E-Abstract |
| 06:00 PM OC7 – Federico Faloci University of Padua Expanding the Therapeutic Potential of Purine C-Nucleosides from Chemical Synthesis to Oligonucleotide Incorporation Author Information & E-Abstract |
| 06:15 PM – Flash Poster communications |
| 07:30 PM – Welcome Cocktail & Dinner |
Thursday, May 21
| 08:30 AM- Invited Lecture Prof. Ana Martinez “TDP-43 Modulation in ALS: From Bench to Bedside” |
| 09:15 AM OC8 – Bárbara Albuquerque University of Porto Evaluation of mitochondrial toxicity induced by a novel COMT inhibitor Author Information & E-Abstract |
| 09:30 AM OC9 – Ayesha Asim Medical University of Lublin Dual-Target Drug Discovery in Alzheimer’s Disease Using Machine Learning guided approach integrated with structure based virtual screening Author Information & E-Abstract |
| 09:45 AM OC10 – Claudia Machado University of Porto Nanocarrier-Based Co-Delivery of Edaravone and Riluzole for Improved ALS Treatment Strategies Author Information & E-Abstract |
| Coffee Break & Poster Session |
| 11:00 AM OC11 – Alice Fossati University of Pavia Identification of Natural Tyrosinase Inhibitors as potential therapy for Neurodegenerative Diseases Author Information & E-Abstract |
| 11:15 AM OC12 – Mariana Castelôa University of Porto Chasing NOX4: From VAS2870 to a Potent, Selective, Covalent Inhibitor Author Information & E-Abstract |
| 11:30 AM OC13 – Manuel Novás Universidade de Santiago de Compostela Pharmacomodulation of 2-Amidobenzothiazoles for the Development of Neuroprotective Compounds: A Phenotypic Study in an Alzheimer’s Disease Model Author Information & E-Abstract |
| 11:45 AM OC14 – Carla Lima University of Porto Targeting Mitochondrial Iron Dysregulation in Friedreich’s Ataxia Using Novel Chelators Author Information & E-Abstract |
| 12:00 PM OC15 – Vince Bart Cardenas Università della Svizzera Italiana Beyond the 1:1 Ligand-Protein Paradigm: An In Silico Assay for Competitive Ligand Binding Author Information & E-Abstract |
| 01:00 PM – Lunch and Relax Time (Before Lunch Group Photo) |
| 02:30 PM– PE Board Meeting |
| 03:15 PM – Invited Lecture Dr. Ed J. Griffen “The discovery of new orally active direct-acting antivirals for lethal Coronaviruses” |
| 04:00 PM OC16 – Caterina Deruvo Università degli Studi di Bari “A. Moro” Investigation of novel guaiacol-bearing molecules as multi-targeted directed ligands (MTDLs) against Alzheimer’s disease-related targets Author Information & E-Abstract |
| 04:15 PM OC17 – Fabiana Lo Mascolo University of Palermo Prodrug strategies to improve the drug-like properties of fragment-derived Keap1-Nrf2 Inhibitors Author Information & E-Abstract |
| 04:30 PM OC18 – Ruben Tack Ghent University Towards Closed-Loop Spatiotemporal Treatment of Drug-Resistant Epilepsy With Photopharmacology Author Information & E-Abstract |
| Coffee Break & Poster Session |
| 05:15 PM OC19 – Nicolò Dal Ponte University of Padova Targeting the vimentin-G4 repeats axis to disrupt EMT and cancer cell invasion Author Information & E-Abstract |
| 05:30 PM OC20 – Marta Duran Martinez Universidad de Alcalá New PROTAC approaches targeting the pseudokinase ILK Author Information & E-Abstract |
| 05:45 PM OC21 – Marzia Fois University of Ljubljana, Faculty of Pharmacy, Slovenia Targeting Mitochondrial KV1.3 in Cancer: Development of Mitochondria-Directed Inhibitors Author Information & E-Abstract |
| 06:00 PM OC22 – Angela Santo University of Bari Integrating Medicinal Chemistry and Bioinformatics to Advance Knowledge on P2X7R in Neuroinflammation and Tumor Immunity Author Information & E-Abstract |
| 06:15 PM OC23 – Francesco Brogi University of Perugia Chemical Probes for Mono-ADP-Ribosylating enzymes (mono-ARTs) inhibition and degradation Author Information & E-Abstract |
| 08:00 PM – Gala Dinner at the Wild Duck Restaurant |
Friday, May 22
| 09:00 AM- Keynote (20 min + Q&A) Prof. Alessandra Montalbano University of Palermo, Italy “Thiazole-Based Derivatives as a Versatile Scaffold in the Inhibition of Respiratory Viruses” |
| 09:30 AM OC24 – Martina Garbagnoli University of Pavia BRAC ligands: novel small molecules targeting the HuR-RNA complexes with a broad-spectrum anticancer activity Author Information & E-Abstract |
| 09:45 AM OC25 – Emiliano Paradiso University of Ljubljana, Faculty of Pharmacy, Slovenia Conjugated NOD1/PRR Agonists Reveal Distinct In Vitro and In Vivo Immune Signatures Author Information & E-Abstract |
| 10:00 AM OC26 – Emanuele Fabbrizi Sapienza University of Rome, Italy Targeting m6A Epitranscriptomic Machinery: Design and Biological Characterization of Potent Quinazoline-Derived METTL3–METTL14 Inhibitors Author Information & E-Abstract |
| 10:15 AM OC27 – Anouk Van Hauwermeiren Ghent University Macrocyclization as a strategy for optimizing PROTACs targeting Aurora Kinase A Author Information & E-Abstract |
| Coffee Break |
| PE-Alumni networking presentation & PE-Medchem Euro PhD Label Communications (15 +3 min Q&A) |
| 11:10 AM PE Award 1 – Laura Marquez-Cantudo Departamento de Química y Bioquímica, Facultad de Farmacia, Universidad San Pablo-CEU, Spain Computer-aided drug design and evaluation of enzyme inhibitors, PROTACs and LYTACs targeting cancer and other diseases Author Information & E-Abstract |
| 11:30 AM PE Award 2 – Giorgio Buttitta Sapienza University of Rome, Italy Liposomes: the gold standard in drug delivery technology Author Information & E-Abstract |
| 11:50 AM PE Award 3 – Adriana Gargano Università Magna Graecia di Catanzaro – Italy Discovery and Characterization of Natural Compounds for Cancer Therapy: A Combined Target-Based and Phenotypic Approach Author Information & E-Abstract |
| 12:10 PM PE Award 4 – Bárbara Nunes LEPABE, ALiCE, Faculty of Engineering, University of Porto, Portugal Quaternary ammonium and phosphonium salts as antimicrobial agents: synthesis, biological evaluation, and mechanistic insights Author Information & E-Abstract |
| 12:30 PM PE Award 5 – Emanuela Marchese Università Magna Graecia di Catanzaro – Italy In Silico Approaches to Uncover the Antioxidant and Therapeutic Properties of Polyphenols Author Information & E-Abstract |
| 01:00 PM – Lunch |
| 02:30 PM PE Award 6 – Yushun Ihor Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Ukraine Synthesis and biological activity of thiazolidine derivatives with a pyrazoline fragment in molecules Author Information & E-Abstract |
| 02:50 PM PE Award 7 – Martina Piga University of Ljubljana, Faculty of Pharmacy, Slovenia Targeting NaV and HV1 channels: discovery of novel small-molecule inhibitors Author Information & E-Abstract |
| 03:10 PM PE Award 8 – Miguel Pinto RISE-Health, Faculty of Medicine, University of Porto, Porto, Portugal Using a nanomedicine-based approach as a second chance for tolcapone Author Information & E-Abstract |
| 03:30 PM PE Award 9 – Lorenzo Raffellini University of Pisa, Italy Targeting autophagy through AMPK: design, synthesis, and biological evaluation of novel allosteric modulators Author Information & E-Abstract |
| 03:50 PM PE Award 10 – Benedetta Salvucci National Center Rare Diseases, Istituto Superiore di Sanità, Rome, Italy Development of Novel Antimalarial Transmission Blocking Agents and Genetic Characterization of Drug Resistance in Mycobacterium abscessus Author Information & E-Abstract |
| Awards and Closing Remarks |
| Social Event |
Secretariat
Contacts
Department of Life and Environmental Sciences (DiSVA)
University of Cagliari
Cittadella Universitaria
09042 Monserrato (CA)
phone +39 070 675 6812 / +39 070 675 6839
Email: medchempe2026@unica.it
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