Preliminary Program
September 24
16:00～17:00 Registration
16:45 Welcome to participants and program presentation: Alessandra Pani, Gianluigi Zanusso
17:00 Welcome from Andrea Sbarbati, Chief of the Department of Neurosciences, Biomedicine and Movement Sciences
Opening lectures:
17:15～18:00 Marina Bentivoglio (UniVr, Verona) “Thalamus in flame”
18:00～18:45 Bernardino Ghetti (Indiana University, USA)
19:30 Apericena (Hotel Tripoli)
September 25
Prion and Prion-Like disorders: Biology
Morning session 8:30～13:30
Chairs: Marina Bentivoglio and Emanuele Buratti
8:30～9:15 Giuseppe Legname (SISSA, Trieste) “Prion”
9:15～10:00 Chiara Zurzolo (Institut Pasteur, Paris) “Cell Biology of prions and nanotubes”
10:00～10:45 Maria Grazia Spillantini (University of Cambridge) “Alfa-synuclein and alfa-synucleinopathies”
10:45～11:00 Coffee Break
11:00～11:45 Emanuele Buratti (ICGEB, Trieste) “TDP-43”
11:45～12:30 Claudio Russo (UniMol, Molise) “Amyloid Beta and Tau”
12:30～13:15 Raffaella Mariotti (UniVr, Verona) “In vitro models of ALS”
Discussion
13:30～14:30 Lunch
Afternoon session 15:00～17:30
Ph.D. Students oral presentations
Chairs: Alessandra Pani and Emanuele Buratti
15:00～15:20 Giulia Salzano (SISSA, Trieste) “Structural studies on the fifth copper binding site in different mammalian prion proteins: new insights into specie barriers”
Discussion
15:20～15:40 Kate Pischke (SISSA, Trieste) “Identifying molecular determinants of prion conversion”
Discussion
15:40～16:00 Clara Grudina (Institut Pasteur, Paris) “Wild type and pathological A53T- α–syn transmission mechanism using human iPSC-derived neurons”
Discussion
16:00～16:20 Anna Pepe (Institut Pasteur, Paris) “Mechanisms of intercellular propagation of aggregated proteins: role of tunneling nanotubes and possible therapeutical approaches”
Discussion
16:20～16:40 Idris Azeez (University of Verona, Italy) “Progression of Aβ deposition and microglia activation in a mouse model of Alzheimer’s disease”
Discussion
16:40～17:00 Lorenzo Brozzetti (University of Verona, Italy) “Neurodegeneration Associated-Proteins in Human Olfactory Neurons”
20:00 Dinner and wine tasting
September 26
Morning session 8:30～13:15
Human Prion and Prion-Like disorders: Amyloid
Chairs: Giuseppe Legname and Claudio Russo
8:30～9:15 Stefano Capaldi (UniVr, Verona) “Protein aggregation and fibrillation”
9:15～10:00 Giuseppe Legname (SISSA, Trieste) “Structure”
10:00～10:45 Fabrizio Tagliavini (Carlo Besta Institute, Milan) “Properties and amyloid disease-associated”
10:45～11:00 Coffee Break
Discussion
Human Prion and Prion-Like disorders: Amyloid assays
Chairs: Maurizio Pocchiari and Gianluigi Zanusso
11:30～12:00 Marina Cucca (AOUI, Verona): “Amyloid and Tau PET”
12:00～12:30 Fabio Moda (Carlo Besta Institute, Milan) “PMCA”
12:30～13:00 Matilde Bongianni (UniVr, Verona) “RT-QuIC”
13:00～13:30 Sarah Vascellari (UniCa, Cagliari) “Recent advances and methodology”
14 :30～19:00 Boat trip to Sirmione and guided visit to Catullo’s villa
September 27
Morning session 8:30～13:00
Human Prion and Prion-Like disorders: Clinical and Molecular Neuropathology
Chairs: Massimo Tabaton and Salvatore Monaco
8:30～9:15 Bernardino Ghetti (Indiana University, USA) “FTLD: tauopathies and non-tauopathies”
9:15～10:00 Maria Grazia Spillantini (University of Cambridge) “Molecular features of Tau”
10:00～10:45 Salvatore Monaco (UniVr, Verona) “Fronto-temporal Dementias”
10:45～11:00 Coffee Break
11:00～11:45 Fabrizio Tagliavini (Carlo Besta Institute, Milan) “Alzheimer”
11:45～12:15 Sergio Ferrari (UniVr, Verona) “Atypical Dementias and co-pathology”
12:15～13:00 Annachiara Cagnin (UniPd, Padua) “Clinical and molecular aspects of Lewy body Dementia”
Discussion
13:00～14:30 Lunch
Afternoon session 15:00～17:00
Atypical variants of prion-like disorders
Chairs: Maurizio Pocchiari and Sergio Ferrari
15:00～15:30 Stefano Tamburin (UniVr, Verona) “Parkinsonisms”
15:30～16:00 Massimo Tabaton (UniGe, Genoa) “Alzheimer”
16:00～16:30 Gianluigi Zanusso (UniVr, Verona) “CJD”
17:00～21:00 Walking session on the beach. Dinner at Hotel Europa
September 28
Morning session 8:30～9:15
Animal Prion and Prion-Like disorders: Animal prion Diseases and animal models
Chairs: Lorenzo Capucci and Sylvie Benestad
8:30～9:15 Giuseppe Ru (IZSTo, Turin) “Epidemiology of animal prion disorders”
9:15～10:00 Cristina Casalone (IZSTo, Turin) “BSE”
10:00～10:45 Sylvie Benestad (University of Oslo) “CWD”
10:45～11:00 Coffee Break
10:00～10:45 Ciriaco Ligios (IZS, Sassari) “Scrapie”
11:00～11:45 Michele di Bari (ISS, Rome) “Voles”
11:45～12:15 Gianluigi Zanusso (UniVr, Verona) “Zoonosis”
Discussion
13:00～14:00 Lunch
Afternoon session 15:00～18:15
Unsolved issues and future perspectives
Chairs: Maurizio Pocchiari and Gianluigi Zanusso
15:00～15:45 Maurizio Pocchiari (ISS, Rome) “CJD”
15:45～16:30 Veronica Redaelli (Carlo Besta Institue, Milan) “Preventive therapy in genetic prion disorders”
16:30～17:15 Giuseppe di Fede (Carlo Besta Institue, Milan) “Genetic resistance to AD”
17:15～18:00 Emiliano Biasini (UniTn, Trent) “Experimental therapy”
18:15 Closing remarks: Alessandra Pani and Gianluigi Zanusso
20:00 Gala Dinner