{"id":45,"date":"2025-04-08T19:49:19","date_gmt":"2025-04-08T17:49:19","guid":{"rendered":"https:\/\/sites.unica.it\/stopme-project\/?page_id=45"},"modified":"2025-04-08T20:28:22","modified_gmt":"2025-04-08T18:28:22","slug":"goals","status":"publish","type":"page","link":"https:\/\/sites.unica.it\/stopme-project\/goals\/","title":{"rendered":"Goals"},"content":{"rendered":"\n<p>Rett syndrome is a rare neurodevelopmental disorder of genetic origin, discovered in 1965 by Dr. Rett, who observed peculiar stereotyped hand movements in some young girls. These patients are not self-sufficient and have an intrinsic structural and functional fragility. A distinctive feature of the syndrome is the presence of stereotypies\u2014repetitive movements triggered by excitement or emotional stress but also present regardless of a cause\u2014that mostly involve the hands and mouth, and could need to be controlled to prevent involuntary self-injury.<\/p>\n\n\n\n<p>Stereotypies may or may not be associated with abnormal breathing patterns, which can include rapid breathing, hyperventilation, or apnea, with potential cardiovascular impact.<\/p>\n\n\n\n<p>The main objectives are:<\/p>\n\n\n\n<p><strong>O1<\/strong>. Development of a compact wearable system for sensing biopotentials and deformations, based on custom textile\/epidermal technologies and both commercial and custom electronics for data acquisition and transmission, also integrating inertial sensors for motion detection.<\/p>\n\n\n\n<p><strong>O2<\/strong>. Training of artificial intelligence capable of locally recognizing the onset of motor or respiratory stereotypies.<\/p>\n\n\n\n<p><strong>O3<\/strong>. Integration of simple actuators to stimulate the interruption of the stereotypy.<\/p>\n\n\n\n<p><strong>O4<\/strong>. Development of an integrated demonstrator tested in the field.<\/p>\n\n\n\n<p><strong>O5<\/strong>. Technical and economic feasibility study (through proof-of-concept support) of an integrated interactive environment designed to assist individuals with Rett syndrome by helping them interrupt stereotypies even in the temporary absence of a caregiver, and in a more effective way.<\/p>\n\n\n\n<p><strong>O6<\/strong>. Study of similar use cases to extend the system to other conditions of vulnerability caused by chronic or neurodegenerative diseases.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1004\" height=\"81\" src=\"http:\/\/sites.unica.it\/stopme-project\/files\/2025\/04\/Logo_firma.png\" alt=\"Logo firma\" class=\"wp-image-35\" srcset=\"https:\/\/sites.unica.it\/stopme-project\/files\/2025\/04\/Logo_firma.png 1004w, https:\/\/sites.unica.it\/stopme-project\/files\/2025\/04\/Logo_firma-300x24.png 300w, https:\/\/sites.unica.it\/stopme-project\/files\/2025\/04\/Logo_firma-768x62.png 768w\" sizes=\"auto, (max-width: 1004px) 100vw, 1004px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Rett syndrome is a rare neurodevelopmental disorder of genetic origin, discovered in 1965 by Dr. Rett, who observed peculiar stereotyped hand movements in some young girls. These patients are not self-sufficient and have an intrinsic structural [&hellip;]<\/p>\n","protected":false},"author":1910,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-45","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.unica.it\/stopme-project\/wp-json\/wp\/v2\/pages\/45","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.unica.it\/stopme-project\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.unica.it\/stopme-project\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.unica.it\/stopme-project\/wp-json\/wp\/v2\/users\/1910"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.unica.it\/stopme-project\/wp-json\/wp\/v2\/comments?post=45"}],"version-history":[{"count":2,"href":"https:\/\/sites.unica.it\/stopme-project\/wp-json\/wp\/v2\/pages\/45\/revisions"}],"predecessor-version":[{"id":64,"href":"https:\/\/sites.unica.it\/stopme-project\/wp-json\/wp\/v2\/pages\/45\/revisions\/64"}],"wp:attachment":[{"href":"https:\/\/sites.unica.it\/stopme-project\/wp-json\/wp\/v2\/media?parent=45"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}