The project
The project “Supporting Termination Of stereotyPies in patients with rett syndroME by advanced ambient intelligence – STOPme” aims to evaluate in real time the state of psychomotor activation of the patient with RETT syndrome, monitoring the onset of neuromotor stereotypies and patterns of hypo- and hyper-ventilation and then conditioning the patient to interrupt the stereotypies by environmental activation. The approach could be easily extendable to other neurodevelopment disorders with similar symptoms.
General aim
To develop a wearable system for multimodal sensing (biopotentials, respiration, and biomechanical parameters) combined with artificial intelligence, capable of detecting motor stereotypies and abnormal cardiorespiratory patterns in patients affected by Rett syndrome, activating the environment (lights and sounds, as well as haptic feedback) to interrupt them and modulate cardiovascular parameters.
Expected results
Technological results: integrated multimodal recording system with edge AI, and the concept of an intelligent environment for the interruption of stereotypies.
Scientific outcomes: multimodal dataset for the characterization of stereotypies in Rett syndrome; characterization of respiratory and cardiovascular patterns in these patients; evaluation of the impact of automated solutions for the termination of stereotypies.
Although designed for Rett syndrome, the system will be adaptable to other conditions.
