{"id":34,"date":"2025-07-23T10:46:55","date_gmt":"2025-07-23T08:46:55","guid":{"rendered":"https:\/\/sites.unica.it\/pe2026\/?page_id=34"},"modified":"2026-05-07T15:05:21","modified_gmt":"2026-05-07T13:05:21","slug":"programme","status":"publish","type":"page","link":"https:\/\/sites.unica.it\/pe2026\/programme\/","title":{"rendered":"Programme"},"content":{"rendered":"\n
\n\n\n\n

Registration opens at 12:00 PM. The event begins at 02:45 PM, with the Plenary Lecture at 03:00 PM. <\/strong><\/p>\n\n\n\n

Wednesday, May 20<\/summary>\n
From 12:00 PM- Registration<\/td><\/tr>
02:45 PM- Welcome & Opening PE2026<\/em> – <\/strong>SALA NAUTILUS<\/td><\/tr>
03:00 PM<\/em><\/strong>– Plenary Lecture<\/em><\/strong>
Prof. Dr. Danijel Kikelj<\/strong> – “Paul Ehrlich MedChem Euro-PhD Network: A Permanent Inspiration”<\/td><\/tr>
Oral Communications<\/em><\/strong><\/em><\/strong> (10 + 3 min Q&A)<\/td><\/tr>
04:00<\/em><\/strong> PM<\/em><\/strong>
OC1<\/em> –<\/em><\/strong><\/strong> Ewout Van de Velde<\/strong>
Ghent University
Generalized parallel synthesis and anti-trypanosomal evaluation of a chemically diverse 6-functionalized C-nucleoside compound library
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
04:15 PM<\/em><\/strong><\/em><\/strong>
OC2<\/em><\/strong> –<\/strong> Ana Carolina Mazzochi<\/strong>
Universidade de Santiago de Compostela
Anti-Trypanosoma cruzi Potential of New Pyrazole-Imidazoline Derivatives<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
04:30<\/em><\/strong> PM<\/em><\/strong>
OC3<\/em><\/strong> – <\/em>Sara Damiani<\/strong>
University of Ljubljana
Synthesis and Investigation of Fluorinated Scaffolds Exhibiting  Through-Space Scalar 19<\/sup>F \u201319<\/sup>F NMR Coupling<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
04:45<\/em><\/strong> PM<\/em><\/strong>
OC<\/em>4<\/strong> – <\/em>Jo\u00e3o Sousa Janela<\/strong>
Universidade de Coimbra
New O-Prenylated Caffeic Acid Amides with Selective Toxicity Against Trypanosoma cruzi Amastigotes. Design, Synthesis and Structure-Activity Relationships<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
Coffee Break<\/td><\/tr>
05:30 PM<\/em><\/strong><\/em><\/strong>
OC5<\/em><\/strong> – <\/em><\/strong> Laura Demuru<\/strong>
University of Cagliari
Identification, Design, and Optimization of New Allosteric Inhibitors Against ZIKV and WNV NS2B-NS3pro<\/sup>
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
05:45<\/em><\/strong> PM<\/em><\/strong>
OC6<\/em><\/strong> – <\/em>Leonardo Lemos<\/strong>
University of Santiago de Compostela
Synthesis, characterization and evaluation of anti-T. cruzi activity of 1-arylpyrazole-4-carboximade-N-propylimidazoles<\/em>
 <\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
06:00<\/em><\/strong> PM<\/em><\/strong>
OC7<\/em><\/strong> –<\/em><\/strong> Federico Faloci<\/strong>
University of Padua
Expanding the Therapeutic Potential of Purine C-Nucleosides from Chemical Synthesis to Oligonucleotide Incorporation<\/em>
 <\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
06:15 PM<\/em><\/strong><\/em><\/strong> – Flash Poster communications<\/em><\/strong><\/td><\/tr>
07:30 PM<\/strong> – Welcome Cocktail & Dinner<\/strong><\/td><\/tr><\/tbody><\/table><\/div><\/figure>\n<\/details>\n\n\n\n
Thursday, May 21<\/summary>\n
08:30 AM- Invited Lecture
<\/em>Prof. Ana Martinez<\/strong>
“TDP-43 Modulation in ALS: From Bench to Bedside”<\/em><\/td><\/tr>
09:15<\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC8<\/em><\/strong><\/em><\/strong> –<\/em><\/strong><\/em><\/strong> B\u00e1rbara Albuquerque<\/strong>
University of Porto
Evaluation of mitochondrial toxicity induced by a novel COMT inhibitor<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
09:30<\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC9 –<\/em><\/strong><\/em> Ayesha Asim<\/strong>
Medical University of Lublin
Dual-Target Drug Discovery in Alzheimer\u2019s Disease Using Machine Learning guided approach integrated with structure based virtual screening
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
09:45<\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC10<\/em><\/strong><\/em> –<\/em><\/strong><\/em><\/strong><\/strong> Claudia Machado<\/strong>
University of Porto
Nanocarrier-Based Co-Delivery of Edaravone and Riluzole for Improved ALS Treatment Strategies
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
Coffee Break & Poster Session<\/td><\/tr>
11:00<\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC1<\/em><\/strong>1<\/em><\/strong> – <\/em><\/strong><\/em>Alice Fossati<\/strong>
University of Pavia
Identification of Natural Tyrosinase Inhibitors as potential therapy for Neurodegenerative Diseases<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
11:15<\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC1<\/em><\/strong>2 – <\/em><\/strong><\/em>Mariana Castel\u00f4a<\/strong>
University of Porto
Chasing NOX4: From VAS2870 to a Potent, Selective, Covalent Inhibitor
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
11:30<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC13<\/em><\/strong><\/em><\/strong><\/em><\/strong> – <\/em><\/em>Manuel Nov\u00e1s<\/strong>
Universidade de Santiago de Compostela
Pharmacomodulation of 2-Amidobenzothiazoles for the Development of Neuroprotective Compounds: A Phenotypic Study in an Alzheimer\u2019s Disease Model
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
11:45<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC14<\/em><\/strong><\/em><\/strong> –<\/em><\/strong> <\/em><\/em>Carla Lima<\/strong>
University of Porto
Targeting Mitochondrial Iron Dysregulation in Friedreich\u2019s Ataxia Using Novel Chelators<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
12:00<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC15<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> – <\/em><\/em><\/em><\/em>Vince Bart Cardenas<\/strong>
Universit\u00e0 della Svizzera Italiana
Beyond the 1:1 Ligand-Protein Paradigm:  An In Silico Assay for Competitive Ligand Binding<\/em>
 <\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
01:00 PM<\/em><\/strong> – Lunch and Relax Time (Before Lunch Group Photo)<\/td><\/tr>
02:30 PM<\/em><\/strong>– PE Board Meeting<\/em><\/strong><\/td><\/tr>
03:15 PM<\/em><\/strong><\/em><\/strong> – Invited Lecture<\/em><\/strong>
Dr. Ed J. Griffen<\/strong>
“The discovery of new orally active direct-acting antivirals for lethal Coronaviruses”<\/em><\/td><\/tr>
04:00<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC16<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Caterina Deruvo<\/strong>
Universit\u00e0 degli Studi di Bari “A. Moro”
Investigation of novel guaiacol-bearing molecules as multi-targeted directed ligands (MTDLs) against Alzheimer\u2019s disease-related targets
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
04:15<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC17<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Fabiana Lo Mascolo<\/strong>
University of Palermo
Prodrug strategies to improve the drug-like properties of fragment-derived Keap1-Nrf2 Inhibitors
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
04:30<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC18 –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> Ruben Tack<\/strong>
Ghent University
Towards Closed-Loop Spatiotemporal Treatment of Drug-Resistant Epilepsy With Photopharmacology
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
Coffee Break & Poster Session<\/td><\/tr>
05:15<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC19 – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Nicol\u00f2 Dal Ponte<\/strong>
University of Padova
Targeting the vimentin-G4 repeats axis to disrupt EMT and cancer cell invasion
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
05:30<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC20<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Marta Duran Martinez<\/strong>
Universidad de Alcal\u00e1
New PROTAC approaches targeting the pseudokinase ILK
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
05:45<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC21 – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Marzia Fois<\/strong>
University of Ljubljana, Faculty of Pharmacy, Slovenia
Targeting Mitochondrial KV1.3 in Cancer: Development of Mitochondria-Directed Inhibitors
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
06:<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong>00<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC22<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Angela Santo<\/strong>
University of Bari
Integrating Medicinal Chemistry and Bioinformatics to Advance Knowledge on P2X7R in Neuroinflammation and Tumor Immunity
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
06:15<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
OC23 – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Francesco Brogi<\/strong>
University of Perugia
Chemical Probes for Mono-ADP-Ribosylating enzymes (mono-ARTs) inhibition and degradation
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
08:00 PM<\/strong><\/em> – Gala Dinner <\/em>at the Wild Duck Restaurant<\/td><\/tr><\/tbody><\/table><\/div><\/figure>\n<\/details>\n\n\n\n
Friday, May 22<\/summary>\n
09:00 AM- Keynote<\/em><\/strong> (20 min + Q&A)
Prof. Alessandra Montalbano
<\/strong>University of Palermo, Italy
\u201cThiazole-Based Derivatives as a Versatile Scaffold in the Inhibition of Respiratory Viruses\u201d<\/em><\/td><\/tr>
09:30<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC24 – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Martina Garbagnoli<\/strong>
University of Pavia
BRAC ligands: novel small molecules targeting the HuR-RNA complexes with a broad-spectrum anticancer activity
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
09:45<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC25<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Emiliano Paradiso<\/strong>
University of Ljubljana, Faculty of Pharmacy, Slovenia
Conjugated NOD1\/PRR Agonists Reveal Distinct In Vitro and In Vivo Immune Signatures
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
10:00<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC26 – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Emanuele Fabbrizi<\/strong>
Sapienza University of Rome, Italy
Targeting m6A Epitranscriptomic Machinery: Design and Biological Characterization of Potent Quinazoline-Derived METTL3\u2013METTL14 Inhibitors
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
10:15<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
OC27 – <\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em>Anouk Van Hauwermeiren<\/strong>
Ghent University
Macrocyclization as a strategy for optimizing PROTACs targeting Aurora Kinase A
<\/em>Author Information & E-Abstract<\/a><\/td><\/tr>
Coffee Break<\/td><\/tr>
PE-Alumni networking presentation &<\/strong><\/em><\/strong> PE-Medchem Euro PhD Label Communications<\/em><\/strong> (15 +3 min Q&A)<\/td><\/tr>
11:10 <\/em><\/strong><\/em><\/strong><\/em><\/strong>AM<\/em><\/strong>
PE Award 1<\/strong><\/em> <\/em><\/strong>–<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Laura Marquez-Cantudo<\/strong>
Departamento de Qu\u00edmica y Bioqu\u00edmica, Facultad de Farmacia, Universidad San Pablo-CEU, Spain
Computer-aided drug design and evaluation of enzyme inhibitors, PROTACs and LYTACs targeting cancer and other diseases<\/em>
 Author Information & E-Abstract<\/a><\/td><\/tr>
11:30<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
PE Award <\/strong><\/em> 2<\/em> <\/em><\/strong>–<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Giorgio Buttitta<\/strong>
Sapienza University of Rome, Italy
Liposomes: the gold standard in drug delivery technology<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
11:50<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> AM<\/em><\/strong>
PE Award <\/strong><\/em> 3 –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Adriana Gargano<\/strong>
Universit\u00e0 Magna Graecia di Catanzaro – Italy
Discovery and Characterization of Natural Compounds for Cancer Therapy: A Combined Target-Based and Phenotypic Approach<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
12:10<\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
PE Award <\/strong><\/em> 4<\/em><\/strong> –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> B\u00e1rbara Nunes<\/strong>
LEPABE, ALiCE, Faculty of Engineering, University of Porto, Portugal
Quaternary ammonium and phosphonium salts as antimicrobial agents: synthesis, biological evaluation, and mechanistic insights<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
12:30<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
PE Award <\/strong><\/em>5<\/em><\/strong> –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Emanuela Marchese<\/strong>
Universit\u00e0 Magna Graecia di Catanzaro – Italy
In Silico Approaches to Uncover the Antioxidant and Therapeutic Properties of Polyphenols<\/em>
 Author Information & E-Abstract<\/a><\/td><\/tr>
01:00<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong> – Lunch<\/td><\/tr>
02:30<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong>
PE Award <\/strong><\/em> 6<\/em><\/strong> –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Yushun Ihor
<\/strong>Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Ukraine
Synthesis and biological activity of thiazolidine derivatives with a pyrazoline fragment in molecules<\/em><\/em>
 Author Information & E-Abstract<\/a><\/td><\/tr>
02:50 PM<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong>
PE Award <\/strong><\/em>7<\/em><\/strong> –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Martina Piga<\/strong>
University of Ljubljana, Faculty of Pharmacy, Slovenia
Targeting NaV and HV1 channels: discovery of novel small-molecule inhibitors<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
03:10<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong>
PE Award<\/strong><\/em> 8<\/em><\/strong> –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Miguel Pinto<\/strong>
RISE-Health, Faculty of Medicine, University of Porto, Porto, Portugal
Using a nanomedicine-based approach as a second chance for tolcapone<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
03:30<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong>
PE Award <\/strong><\/em>9<\/em><\/strong> –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Lorenzo Raffellini<\/strong>
University of Pisa, Italy
Targeting autophagy through AMPK: design, synthesis, and biological evaluation of novel allosteric modulators<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
03:50<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong> PM<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong>
PE Award<\/strong><\/em> 10<\/em><\/strong> –<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em> Benedetta Salvucci<\/strong>
National Center Rare Diseases, Istituto Superiore di Sanit\u00e0, Rome, Italy
Development of Novel Antimalarial Transmission Blocking Agents and Genetic Characterization of Drug Resistance in Mycobacterium abscessus<\/em>
Author Information & E-Abstract<\/a><\/td><\/tr>
Awards and Closing Remarks<\/em><\/strong><\/td><\/tr>
Social Event<\/td><\/tr><\/tbody><\/table><\/div><\/figure>\n<\/details>\n\n\n\n

<\/p>\n\n\n\n

\n\n\n\n

Secretariat<\/h2>\n\n\n\n

Contacts<\/strong>
<\/em>Department of Life and Environmental Sciences (DiSVA)
University of Cagliari
Cittadella Universitaria
09042 Monserrato (CA)
phone +39 070 675 6812 \/ +39 070 675 6839<\/p>\n\n\n\n

Email: medchempe2026@unica.it<\/strong><\/a><\/p>\n\n\n\n

Follow us:<\/strong><\/em><\/p>\n\n\n\n

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Treasuer
<\/em><\/strong>Erica Sanna<\/p>\n","protected":false},"excerpt":{"rendered":"

Registration opens at 12:00 PM. The event begins at 02:45 PM, with the Plenary Lecture at 03:00 PM. Secretariat ContactsDepartment of Life and Environmental Sciences (DiSVA)University of CagliariCittadella Universitaria09042 Monserrato (CA)phone +39 070 675 6812 \/ […]<\/p>\n","protected":false},"author":9643,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-34","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.unica.it\/pe2026\/wp-json\/wp\/v2\/pages\/34","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.unica.it\/pe2026\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.unica.it\/pe2026\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.unica.it\/pe2026\/wp-json\/wp\/v2\/users\/9643"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.unica.it\/pe2026\/wp-json\/wp\/v2\/comments?post=34"}],"version-history":[{"count":88,"href":"https:\/\/sites.unica.it\/pe2026\/wp-json\/wp\/v2\/pages\/34\/revisions"}],"predecessor-version":[{"id":1990,"href":"https:\/\/sites.unica.it\/pe2026\/wp-json\/wp\/v2\/pages\/34\/revisions\/1990"}],"wp:attachment":[{"href":"https:\/\/sites.unica.it\/pe2026\/wp-json\/wp\/v2\/media?parent=34"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}