2024.09.23 – Monday |
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| 15:30 | Shuttle from Hotel Flamingo to the Research Park | |
| 16:30 | Opening Remarks | Auditorium |
| Plenary Lectures | ||
| 17:00-17:45 | Broader-acting antivirals for epidemic and pandemic preparedness | Johan Neyts KU Leuven |
| 17:45-18:30 | A Biochemist’s Journey of Antiviral Drug Discovery | Joy Feng San Francisco, CA |
| 18:30 | Shuttle from Research Park to the Hotel Flamingo | |
| 20:00 | Dinner | |
2024.09.24 – Tuesday |
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| 8:15 | Shuttle from Hotel Flamingo to the Research Park | |
| Plenary Lecture | Auditorium | |
| 9:00-9:45 | Using DNA-Encoded Library Screening to Effectively and Rapidly Develop New Antiviral Drugs | Damian Young Houston TX, USA, |
| 9:45-11:00 | Selected talks – session I O.1-O.6 | |
| O.1 | Design and Synthesis of Novel Macrocycle Inhibitors Targeting SARS-CoV-2 Main Protease | Alessia Alberico UNINA |
| O.2 | Studies on the SARS-CoV-2 Mpro dimerization mechanism using a split luciferase assay | Renee Delgado UT Health |
| O.3 | Discovery of novel non-nucleoside inhibitors against SARS-CoV-2 minimal replication-transcription complex | Paolo Malune UNICA |
| O.4 | The in vitro genetic barrier to resistance of lenacapavir is not affected by viral subtype or heavy treatment exposure | Chiara Paletti UNISI |
| O.5 | New strategies for inhibiting Hepatitis B Virus entry using Cyclosporine A analogues | Marika Longo Minnolo UNIMI |
| O.6 | Exploring thiazole systems for antiviral applications: synthesis and biological evaluation | Roberta Bivacqua UNIPA |
| 11:00 | Coffee Break | |
| Plenary Lecture | Auditorium | |
| 11:30-12:15 | Challenges and opportunities in the management of antiviral drug resistance among DNA viruses | Graciela Andrei KU Leuven |
| 12:15-13:15 | Poster session I – odd numbers | Workshop Room |
| 13:30-14:30 | Lunch | |
| Plenary Lecture | Auditorium | |
| 14:30-15:15 | First in Class and Best in Class in antiviral drug discovery: two different meaning, challenges and opportunities | Vincenzo Summa UNINA |
| 15:15-16:30 | Selected talks – session II 0.7_O.12 | |
| O.7 | Investigating the role of lake microbial enzymes on virus inactivation | Daniela Morales Duran EPFL |
| O.8 | Targeting HSV-1 through FASN inhibitors: implications for Alzheimer’s Disease | Linda Trifirò UNITO |
| O.9 | Novel Fusion Inhibitors Targeting Hemagglutinin (HA) of Influenza A H1N1 Virus | Álvaro de la Cruz CSIC IMQ |
| O.10 | Fusion inhibitory peptides inhibit SARS-CoV-2 Omicron BA.5 transmission in hamsters | Kim Johanna Handrejk Rotterdam |
| O.11 | Elucidation of the pan-flavivirus potential of NS4B-targeting antivirals | Dominik Kiemel CIID |
| O.12 | Exploiting the potency of new DKA derivatives as SARS-CoV-2 nsp13 inhibitors and their role in blocking viral replication | Roberta Emmolo UNICA |
| 16.45 | Shuttle from Research Park to the Hotel Flamingo | |
| 18:30 | Discussion Groups | |
| 20:00 | Dinner | |
2024.09.25 – Wednesday |
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| 8:15 | Shuttle from Hotel Flamingo to the Research Park | |
| Plenary Lectures | Auditorium | |
| 9:00-9:45 | Outflanking the Pathogenic Arenaviruses | Brian Gowen Utah, United States |
| 9:45-10:30 | HIV: to integrate, or not to integrate, that is the question | Ben Berkhout Amsterdam UMC, the Netherlands |
| 10:30-11:00 | Selected talks – session III O.13-O.14 | |
| O.13 | Polyoxometalate exerts broad-spectrum activity against human respiratory viruses hampering viral entry | Elisa Feyles UNITO |
| O.14 | A novel class of SARS-COV-2 nsp13 Helicase and NTPase inhibitors: Pyridobenzothiazolone (PBTZ)-based compounds | Anastasia Ferraro UNINA |
| 11:00 | Coffee Break | |
| Plenary Lecture | Auditorium | |
| 11:30-12:15 | Exploiting Ebola virus suppression of the innate immune activation as target for drug development | Angela Corona UNICA |
| 12:15-13:15 | Poster session II – even numbers | Workshop Room |
| 13.30-14.30 | Lunch | |
2024.09.25 – Wednesday |
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| Plenary Lecture | Auditorium | |
| 14:30-15:15 | Flex-Nucleosides – a strategic approach to broad-spectrum antiviral therapeutics | Kathie Seley-Radtke UMBC |
| 15:15-16:30 | Selected talks – session IV 5 O.15- O.20 | |
| O.15 | Amphibian peptide HS-1 and its ala-Scanning analogues as broad-spectrum antivirals | Bianca Maria Nastri UNICM |
| O.16 | Multi-Omics Profiling to Unveil West Nile Virus interactions with Infected cells | Sante Scognamiglio UNICA |
| O.17 | Discovery of thioaryl imides as a new family of SARS-CoV-2 entry inhibitors | Víctor Fernández Cabello CSIC |
| O.18 | Molecular evolution of the hepatitis B virus in the presence of some promising antiviral plant extract formulations | Giscard Wilfried Koyaweda Paul-Ehrlich-Institut |
| O.19 | Prevention of lethal SARS-CoV-2 replication in human ACE2-transgenic mice through error prone suggests that daclatasvir dose can be adjusted for early COVID-19 therapy | Mayara Mattos IOC Fiocruz/Brazil |
| O.20 | Evaluation of broad-spectrum piperazine-based compounds able to inhibit flavivirus and/or SARS-CoV-2 replication in a live virus assay | Ilenia Varasi UNISI |
| 16.30 | Shuttle from Research Park to the Hotel Flamingo | |
| 18:30 | Discussion Groups | |
| 20:00 | Dinner | |
2024.09.26 – Thursday |
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| 8:15 | Shuttle from Hotel Flamingo to the Research Park | |
| Scientific event : “Public/private synergies in viral research” | Auditorium | |
| 9:00-9:45 | Development of immunotherapy based on genetically delivered Human endogenous retrovirus-K based VLPs | Peter J. Holst Hervolution |
| 9:45-10:30 | Data informed drug discovery, software tools and case studies | Philip Gribbon Fraunhofer Inst. |
| 10:30 | Coffee Break | |
| 11:00-12:30 | Round table “Is there life after the PhD?”
Peter J. Holst Hervolution |
Auditorium |
| 12.30-14:00 | Lunch | |
| 14:00-14:20 | Roberto Anedda (Porto Conte Ricerche): NMR in antiviral drug discovery: the project of the NMR Platform in Sardinia | |
| 14:20-14:50 | Ilaria Trudu (Sardegna Ricerche): International opportunities for research and innovation, the role of the Enterprise Europe Network (EEN Network) | |
| 14:50-15:10 | Akash Deep Bisvas (Dompè Pharmaceuticals): The LIGATE Project: Harnessing AI for Advanced Drug Discovery Against Viral Infections | |
| 15:10-15:40 | Emanuela D’Acunto: (Takis Biotech) :Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein | |
| 15.30-16.15 | Franco Lori (Virostatics): Revamping Sanitation: How SARS-CoV-2 Has Elevated the Role of Biocides in Closed Environments | |
| 16:15-17:30 | Round table «Opportunities for Regional development of Biotech research»
Peter J. Holst Hervolution |
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| 17:30 | Shuttle from Research Park to the Hotel Flamingo | |
| 20:00 | Dinner | |
2024.09.27 – Friday |
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| 8:15 | Shuttle from Hotel Flamingo to the Research Park | |
| Plenary Lectures | Auditorium | |
| 9:00-9:45 | Innovative strategies for antiviral development: from viral RNA to attachment mimicry | Valeria Cagno CHUV |
| 9:45-10:30 | Anthranilic Acid based Dihydroorotate Dehydrogenase Inhibitors for the Use as Antiviral Agents | Chris Meier Hamburg University |
| 10:30 | Coffee Break | |
| Plenary Lectures | Auditorium | |
| 10:30-12:15 | Cellular APOBEC3 enzymes and herpesviruses – why we should care! | Reuben Harris UT Health |
| 12:15-13:15 | Poster session III- All | Workshop Room |
| 13:15-14.30 | Lunch | |
| Plenary Lecture | Auditorium | |
| 14:30-15:15 | Tools and Tactics for Targeting RNA with Small Molecules | Jay Schneekloth NIH Frederick |
| 15:15-16:10 | Selected talks – session V O.21 – O.24 | |
| O.21 | AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospHolIpidosis | Maria Cristina Lomuscio UNIBA |
| O.22 | Plant-derived Antiviral Strategies: Antiherpetic Properties of Tomato Root Exudate and Antimicrobial Efficacy of Soybean-Derived plasticizer | Greta Bajetto UNIPO |
| O.23 | Structural and Functional Characterization of Receptor Binding Domain (RBD) for the reconstructed HERV Envelopes and their interaction with Host Cellular Receptors | Saili Chabukswar UNICA |
| O.24 | Advancing Nanoparticle-Based Delivery Systems for Antiviral Agents | Mayra Castañeda Cataña, CONICET |
| 16:15 | Shuttle from Research Park to the Hotel Flamingo | |
| 18:00 | Not only science: traditional volleyball match! | |
| 20:00 | Closing dinner | |