Project title: Engineering physiologically and pathologically relevant organ Models for the Investigation of Age related Diseases (Ingegnerizzazione di Modelli d’organo di interesse fisiologico e patologico per l’INdagine di Disturbi legati all’invecchiamento)
Project Acronym: MIND
Years: 2013-2016

Project description

The MIND project aims at overcoming the current lack of models for the study of the physiological conditions associated with aging through the development –by advanced bioengineering technologies- of in vitro dynamic models, able to reproduce the physio-pathological conditions of aged tissues, while respecting the 3 Rs (“Replacement, Refinement, Reduction”) principle of animal testing.

The multidisciplinary consortium, composed mainly of bioengineers, flanked by clinicians, biologists, experts in the regulatory aspects of health and physical and electronic engineers, will pool its varied expertise and knowledge to design, realize, model and characterize new systems for the investigation of ageing and age related diseases, with reference to four tissues which are particularly compromised by age related degeneration: cardiac, bone, epithelial and neural tissue.

The project represents a first step towards the long-term goal of generating reliable biomimetic models of tissues for the study of pathological conditions and the development of pharmacological strategies, reducing animal and clinical testing, as well as the time and costs associated with them.

Project details

Project Acronym: MIND
Start Date: 2013-02-01
Duration: 36 months
End Date: 2016-02-01
Project Funding: 1260000 euro
Project Funding for Università degli Studi di Cagliari: 63000 euro


Politecnico di Torino – Dipartimento di Ingegneria Meccanica E Aerospaziale
Università Campus Bio-Medico di Roma – Centro Integrato Di Ricerca (C.I.R.)
Università degli Studi di Torino – Dipartimento di Genetica, Biologia E Biochimica
Consiglio Nazionale delle Ricerche Istituto di fisiologia clinica
Politecnico di Milano – Dipartimento di Ingegneria  Strutturale
Università della Calabria – Dipartimento di Ingegneria Chimica E Dei Materiali ITALY
Università degli Studi di Cagliari – Dipartimento di Ingegneria Elettrica Ed Elettronica
Università degli Studi di Bologna – Dipartimento di Fisica
Università Politecnica delle Marche – Dipartimento Di Scienze Cliniche E Molecolari
credits | accessibilità Università degli Studi di Cagliari
C.F.: 80019600925 - P.I.: 00443370929
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